Pdcd10^tm1Arte
Targeted Allele Detail

Summary

• Symbol: Pdcd10^tm1Arte
• Name: programmed cell death 10; targeted mutation 1, TaconicArtemis
• MGI ID: MGI:5297592
• Synonyms: Ccm3^fl
• Gene: Pdcd10 Location: Chr3:75423797-75464159 bp, - strand Genetic Position: Chr3, 33.76 cM, cytoband E3
• Alliance: Pdcd10^tm1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:177584
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Two P-lox sequences were inserted that flank exons 4 and 5 of the murine Pdcd10 gene. (J:229615)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdcd10 Mutation: 20 strains or lines available

References

• Original: J:177584 Boulday G, et al., Developmental timing of CCM2 loss influences cerebral cavernous malformations in mice. J Exp Med. 2011 Aug 29;208(9):1835-47
• All: 5 reference(s)