Vsig1^tm1Imad
Targeted Allele Detail

Summary

• Symbol: Vsig1^tm1Imad
• Name: V-set and immunoglobulin domain containing 1; targeted mutation 1, Ibrahim M Adham
• MGI ID: MGI:5297726
• Gene: Vsig1 Location: ChrX:139808357-139840221 bp, + strand Genetic Position: ChrX, 61.62 cM, cytoband F1
• Alliance: Vsig1^tm1Imad page

Mutation origin

• Mouse Generated: Earliest citation of chimera generation: J:178119
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Exon 1a was replaced with a neo cassette. (J:178119)

Generatio of the Vsig1^tm1Imad allele

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vsig1 Mutation: 16 strains or lines available

Notes

Very low chimerism is seen and surviving mice fail to produce germ line transmission of this allele.

References

• Original: J:178119 Oidovsambuu O, et al., Adhesion protein VSIG1 is required for the proper differentiation of glandular gastric epithelia. PLoS One. 2011;6(10):e25908
• All: 1 reference(s)