Prkdc^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Prkdc^m1Btlr
• Name: protein kinase, DNA activated, catalytic polypeptide; mutation 1, Bruce Beutler
• MGI ID: MGI:5299140
• Synonyms: clover
• Gene: Prkdc Location: Chr16:15455730-15660099 bp, + strand Genetic Position: Chr16, 10.09 cM, cytoband B1
• Alliance: Prkdc^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to C transversion at bp 64291 in intron 29, within the donor splice site, 2 nucleotides after exon 29 of the Prkdc mRNA (NCBI RefSeq: NM_011159.2). The point mutation results in the amino acid substitution of isoleucine to threonine at position 1010 (I1010T). (J:178522)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Prkdc Mutation: 417 strains or lines available

References

• Original: J:178522 Beutler B, Direct Data Submission 2011/12/20. MGI Direct Data Submission. 2001
• All: 2 reference(s)