Skor2^{Tn(sb-Tyr)1799B.CA3Ove}
Transposon induced Allele Detail

Summary

• Symbol: Skor2^{Tn(sb-Tyr)1799B.CA3Ove}
• Name: SKI family transcriptional corepressor 2; transposon insertion 1799B.CA3, Paul A Overbeek
• MGI ID: MGI:5300465
• Gene: Skor2 Location: Chr18:76944100-76988037 bp, + strand Genetic Position: Chr18, 51.93 cM
• Alliance: Skor2^{Tn(sb-Tyr)1799B.CA3Ove} page

Mutation origin

• Strain of Origin: FVB/N

Mutation description

• Allele Type: Transposon induced (Inserted expressed sequence)
• Mutation: Transposon insertion
• Mutation details: Mobilization of the transposon from TgTn(sb-Tyr)1799BOve transgenic mice with Sleeping Beauty transposase from Tg(CAG-sb10)1Dla transgenic mice results in the integration of the transposon in exon 2 (77,097,862; [from NCBI37/mm9 (July 2007)]). (J:178818)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Skor2 Mutation: 45 strains or lines available

References

• Original: J:178818 Wang B, et al., Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development. Development. 2011 Oct;138(20):4487-97
• All: 1 reference(s)