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Tg(Oxr1-cre)C14Stl
Transgene Detail
Summary
Symbol: Tg(Oxr1-cre)C14Stl
Name: transgene insertion C14, Susumu Tonegawa
MGI ID: MGI:5300944
Synonyms: p(Oxr1-Cre)
Transgene: Tg(Oxr1-cre)C14Stl  Location: unknown  
Alliance: Tg(Oxr1-cre)C14Stl page
Transgene
origin
Strain of Origin:  C57BL/6NTac
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Oxr1-cre)C14Stl expression driven by 1 gene
 
Mutation detailsThe cre recombinase sequence was inserted by BAC recombineering methods into the translation initiation site in exon 2 of the Oxr1 gene in a BAC construct which contained the promoter region, coding sequence and a 50 kb 3' downstream region. The final vector was injected into pronuclei of fertilized C57BL/6 eggs. 16 founders were obtained and crossed with lacZ reporter mice to identify one line which displayed robust recombination in superficial layer III the dorsal portion of the medial entorhinal cortex. (J:178297)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Oxr1 (species not specified)
Summary of all recombinase alleles driven by Oxr1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:178297 Suh J, et al., Entorhinal cortex layer III input to the hippocampus is crucial for temporal association memory. Science. 2011 Dec 9;334(6061):1415-20
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory