S1pr4^tm1Lipp
Targeted Allele Detail

Summary

• Symbol: S1pr4^tm1Lipp
• Name: sphingosine-1-phosphate receptor 4; targeted mutation 1, Martin Lipp
• MGI ID: MGI:5301363
• Gene: S1pr4 Location: Chr10:81333581-81335966 bp, - strand Genetic Position: Chr10, 39.72 cM, cytoband C1
• Alliance: S1pr4^tm1Lipp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:179199
• Parent Cell Line: AV3 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Most of the coding region was replaced with a neo cassette. Western blot analysis confirmed the absence of transcript expression on bone marrow cells. (J:179199)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any S1pr4 Mutation: 20 strains or lines available

References

• Original: J:179199 Golfier S, et al., Shaping of terminal megakaryocyte differentiation and proplatelet development by sphingosine-1-phosphate receptor S1P4. FASEB J. 2010 Dec;24(12):4701-10
• All: 7 reference(s)