Cert1^tm1.1Jsau
Targeted Allele Detail

Summary

• Symbol: Cert1^tm1.1Jsau
• Name: ceramide transporter 1; targeted mutation 1.1, Juan Saus
• MGI ID: MGI:5301370
• Synonyms: gpbp-1^-
• Gene: Cert1 Location: Chr13:96679243-96776675 bp, + strand Genetic Position: Chr13, 50.58 cM
• Alliance: Cert1^tm1.1Jsau page

Deletion of Exon 11 in Col4a3bp to generate the Cert1^tm1.1Jsau allele

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:177789
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Modified isoform(s))
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination removed exon 11 and the neo cassette. Western blot analysis confirmed the expression of isoform 2 but not isoforms 1 and 3. (J:177789)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cert1 Mutation: 28 strains or lines available

References

• Original: J:177789 Revert-Ros F, et al., Goodpasture antigen-binding protein (GPBP) directs myofibril formation: identification of intracellular downstream effector 130-kDa GPBP-interacting protein (GIP130). J Biol Chem. 2011 Oct 7;286(40):35030-43
• All: 1 reference(s)