Oscar^tm1Ywc
Targeted Allele Detail

Summary

• Symbol: Oscar^tm1Ywc
• Name: osteoclast associated receptor; targeted mutation 1, Yongwon Choi
• MGI ID: MGI:5301430
• Gene: Oscar Location: Chr7:3612812-3619156 bp, - strand Genetic Position: Chr7, 2.08 cM
• Alliance: Oscar^tm1Ywc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:178250
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 3.0 kb segment, containing the entire extracellular domain (exon 3 and 4) and transmembrane domain (exon 5), was deleted. (J:178250)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Oscar Mutation: 24 strains or lines available

References

• Original: J:178250 Barrow AD, et al., OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice. J Clin Invest. 2011 Sep 1;121(9):3505-16
• All: 2 reference(s)