Cdkal1^tm1.2Tomik
Targeted Allele Detail

Summary

• Symbol: Cdkal1^tm1.2Tomik
• Name: CDK5 regulatory subunit associated protein 1-like 1; targeted mutation 1.2, Kazuhito Tomizawa
• MGI ID: MGI:5301443
• Gene: Cdkal1 Location: Chr13:29375729-30039657 bp, - strand Genetic Position: Chr13, 12.93 cM, cytoband A3.3
• Alliance: Cdkal1^tm1.2Tomik page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:178248
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: Cre-mediated recombination of Cdkal1^tm1.1Tomik removed exon 5. (J:178248)

Generation of the Cdkal1^tm1.1Tomik and Cdkal1^tm1.2Tomik alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdkal1 Mutation: 60 strains or lines available

References

• Original: J:178248 Wei FY, et al., Deficit of tRNA(Lys) modification by Cdkal1 causes the development of type 2 diabetes in mice. J Clin Invest. 2011 Sep 1;121(9):3598-608
• All: 1 reference(s)