Tg(Crx-cre/ERT2)1Tfur
Transgene Detail

Summary

• Symbol: Tg(Crx-cre/ERT2)1Tfur
• Name: transgene insertion 1, Takahisa Furukawa
• MGI ID: MGI:5302219
• Synonyms: Crx-CreERT2
• Transgene: Tg(Crx-cre/ERT2)1Tfur Location: unknown
• Alliance: Tg(Crx-cre/ERT2)1Tfur page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Crx-cre/ERT2)1Tfur expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Crx

• Mutation details: The 2 kb promoter fragment of Crx drives expression of the tamoxifen-inducible cre/ERT2 fusion sequence in the transgenic construct. (J:177908)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Crx (species not specified) Summary of all recombinase alleles driven by Crx. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:177908 Muranishi Y, et al., An Essential Role for RAX Homeoprotein and NOTCH-HES Signaling in Otx2 Expression in Embryonic Retinal Photoreceptor Cell Fate Determination. J Neurosci. 2011 Nov 16;31(46):16792-807
• All: 5 reference(s)