Pomt2^tm1.2Hhu
Targeted Allele Detail

Summary

• Symbol: Pomt2^tm1.2Hhu
• Name: protein-O-mannosyltransferase 2; targeted mutation 1.2, Huaiyu Hu
• MGI ID: MGI:5302226
• Gene: Pomt2 Location: Chr12:87153635-87194742 bp, - strand Genetic Position: Chr12, 41.3 cM
• Alliance: Pomt2^tm1.2Hhu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:179356
• Parent Cell Line: D2 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6J)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination of Pomt2^tm1.1Hhu removed exons 2 through 4. (J:179356)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pomt2 Mutation: 38 strains or lines available

References

• Original: J:179356 Hu H, et al., Conditional knockout of protein O-mannosyltransferase 2 reveals tissue-specific roles of O-mannosyl glycosylation in brain development. J Comp Neurol. 2011 May 1;519(7):1320-37
• All: 1 reference(s)