Angptl4^tm1Vlcg
Targeted Allele Detail

Summary

• Symbol: Angptl4^tm1Vlcg
• Name: angiopoietin-like 4; targeted mutation 1, Velocigene
• MGI ID: MGI:5302391
• Synonyms: angptl14^LacZ
• Gene: Angptl4 Location: Chr17:33993874-34000549 bp, - strand Genetic Position: Chr17, 17.98 cM
• Alliance: Angptl4^tm1Vlcg page

Perturbation of endothelial junction integrity in Angptl4^tm1Vlcg/Angptl4^tm1Vlcg pups

Show the 4 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:177790
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout, Reporter) Mutations: Insertion, Intragenic deletion The coding region was replaced with a lacZ reporter gene. (J:177790)

Generation of the Angptl4^tm1Vlcg allele

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Angptl4 Mutation: 34 strains or lines available

References

• Original: J:177790 Perdiguero EG, et al., Alteration of Developmental and Pathological Retinal Angiogenesis in angptl4-deficient Mice. J Biol Chem. 2011 Oct 21;286(42):36841-51
• All: 5 reference(s)