Sstr5^tm1Fcb
Targeted Allele Detail

Summary

• Symbol: Sstr5^tm1Fcb
• Name: somatostatin receptor 5; targeted mutation 1, F Charles Brunicardi
• MGI ID: MGI:5303078
• Synonyms: Sstr5^tm1.1Xpw, Sstr5^tm1Kum
• Gene: Sstr5 Location: Chr17:25708849-25716262 bp, - strand Genetic Position: Chr17, 12.62 cM
• Alliance: Sstr5^tm1Fcb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:179577
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A targeting vector containing a neo gene was inserted into the locus via homologous recombination. Southern blot analysis was used to identify successful recombinants. (J:185417)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sstr5 Mutation: 14 strains or lines available

References

• Original: J:179577 Norman M, et al., Sulfonylurea receptor knockout causes glucose intolerance in mice that is not alleviated by concomitant somatostatin subtype receptor 5 knockout. Ann Surg. 2002 Jun;235(6):767-74
• All: 6 reference(s)