Gt(ROSA)26Sor^{tm1(CAG-Bgeo,-Insc/GFP)Jakn}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-Bgeo,-Insc/GFP)Jakn}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Juergen A Knoblich
• MGI ID: MGI:5304351
• Synonyms: R26^ki
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-Bgeo,-Insc/GFP)Jakn} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:178712
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(CAG-Bgeo,-Insc/GFP)Jakn} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Insc (MGI:1917942)

• Mutation details: A targeting construct consisting of CMV enhancer sequence, a beta actin promoter, a floxed beta-geo stop cassette and a mouse Insc-GFP fusion gene was inserted via homologous recombination. (J:178712)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:178712 Postiglione MP, et al., Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex. Neuron. 2011 Oct 20;72(2):269-84
• All: 1 reference(s)