Lim2^Aca47
Chemically induced Allele Detail

Summary

• Symbol: Lim2^Aca47
• Name: lens intrinsic membrane protein 2; ACMaster abnormality 47
• MGI ID: MGI:5304394
• Synonyms: Aca47, Lim2^C51R
• Gene: Lim2 Location: Chr7:43079523-43085420 bp, + strand Genetic Position: Chr7, 28.25 cM
• Alliance: Lim2^Aca47 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis resulted in the transition of T to C that leads to the amino acid substitution of arginine for cysteine at position 51 (C51R). (J:179533)
• Inheritance: Semidominant

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Lim2 Mutation: 15 strains or lines available

References

• Original: J:179533 Puk O, et al., Microphakia and congenital cataract formation in a novel Lim2(C51R) mutant mouse. Mol Vis. 2011;17:1164-71
• All: 1 reference(s)