Lbx1^tm1.1Khan
Targeted Allele Detail

Summary

• Symbol: Lbx1^tm1.1Khan
• Name: ladybird homeobox 1; targeted mutation 1.1, Kazunori Hanaoka
• MGI ID: MGI:5304400
• Synonyms: Lbx1^flox
• Gene: Lbx1 Location: Chr19:45221123-45224251 bp, - strand Genetic Position: Chr19, 38.61 cM, cytoband D
• Alliance: Lbx1^tm1.1Khan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:178868
• Parent Cell Line: TT2F (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. A loxP-IRES-EGFP-FRT-neo-FRT cassette was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette. (J:178868)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lbx1 Mutation: 13 strains or lines available

References

• Original: J:178868 Watanabe S, et al., Generation of a conditional null allele of Lbx1. Genesis. 2011 Oct;49(10):803-10
• All: 2 reference(s)