Pdss2^tm1Jdhu
Targeted Allele Detail

Summary

• Symbol: Pdss2^tm1Jdhu
• Name: prenyl (solanesyl) diphosphate synthase, subunit 2; targeted mutation 1, Jian-Dong Huang
• MGI ID: MGI:5304514
• Synonyms: Pdss2^f-E-Neo
• Gene: Pdss2 Location: Chr10:43097482-43340878 bp, + strand Genetic Position: Chr10, 22.91 cM, cytoband B2
• Alliance: Pdss2^tm1Jdhu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:179845
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked EGFP and neo cassette with a 5' loxP site was inserted downstream of exon 2. (J:179845)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdss2 Mutation: 31 strains or lines available

References

• Original: J:179845 Lu S, et al., Cerebellar defects in Pdss2 conditional knockout mice during embryonic development and in adulthood. Neurobiol Dis. 2012 Jan;45(1):219-33
• All: 1 reference(s)