Gt(ROSA)26Sor^tm1Uga
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm1Uga
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Marcus Fechheimer
• MGI ID: MGI:5304689
• Synonyms: R26CT
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm1Uga page

Hirano Bodies are seen in Gt(ROSA)26Sor^tm1Uga/Gt(ROSA)26Sor^tm1Uga Tg(Thy1-cre)703Vaw/0 mice

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:179833
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A cassette containing a floxed beta-geo-stop and the C-terminal fragment (amino acids 124 to 295) of the Dictyostelium discoideum 34 kDa F-actin bundling protein fused to GFP (CT-GFP) was inserted into the locus. (J:179833)

Targeting strategy of the inducible Gt(ROSA)26Sor^tm1Uga transgene

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:179833 Ha S, et al., Transgenic mouse model for the formation of Hirano bodies. BMC Neurosci. 2011;12:97
• All: 1 reference(s)