Ggps1^tm1Licj
Targeted Allele Detail

Summary

• Symbol: Ggps1^tm1Licj
• Name: geranylgeranyl diphosphate synthase 1; targeted mutation 1, Chao-Jun Li
• MGI ID: MGI:5304847
• Synonyms: Ggpps^fl
• Gene: Ggps1 Location: Chr13:14225244-14238073 bp, - strand Genetic Position: Chr13, 5.29 cM
• Alliance: Ggps1^tm1Licj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:179942
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 3 and 4 were flanked with loxP site. An FRT-flanked neo cassette was also inserted for selection. (J:179942)

Expression

In Mice Carrying this Mutation:

276 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ggps1 Mutation: 25 strains or lines available

References

• Original: J:179942 Yu X, et al., Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice. EMBO J. 2011 Sep 14;30(18):3754-65
• All: 19 reference(s)