Dscam^tm1.1Pfu
Targeted Allele Detail

Summary

• Symbol: Dscam^tm1.1Pfu
• Name: DS cell adhesion molecule; targeted mutation 1.1, Peter G Fuerst
• MGI ID: MGI:5305025
• Synonyms: Dscam^FD
• Gene: Dscam Location: Chr16:96392040-96971952 bp, - strand Genetic Position: Chr16, 57.02 cM, cytoband C
• Alliance: Dscam^tm1.1Pfu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:179393
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 27 was floxed and an inverted FRT flanked neo cassette was inserted downstream of exon 27 via homologous recombination. Cre mediated recombination removed exon 27. (J:179393)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dscam Mutation: 106 strains or lines available

References

• Original: J:179393 Fuerst PG, et al., Cell autonomy of DSCAM function in retinal development. Dev Biol. 2012 Jan 15;361(2):326-37
• All: 7 reference(s)