Pura^tm1Herm
Targeted Allele Detail

Summary

• Symbol: Pura^tm1Herm
• Name: purine rich element binding protein A; targeted mutation 1, Jochen Herms
• MGI ID: MGI:5305287
• Gene: Pura Location: Chr18:36414150-36425588 bp, + strand Genetic Position: Chr18, 19.46 cM, cytoband B3
• Alliance: Pura^tm1Herm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:179606
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The open reading frame was replaced with a neo cassette. (J:179606)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pura Mutation: 26 strains or lines available

References

• Original: J:179606 Hokkanen S, et al., Lack of Pur-alpha alters postnatal brain development and causes megalencephaly. Hum Mol Genet. 2012 Feb 1;21(3):473-84
• All: 1 reference(s)