Jup^tm1.1Tmj
Targeted Allele Detail

Summary

• Symbol: Jup^tm1.1Tmj
• Name: junction plakoglobin; targeted mutation 1.1, Thomas M Jessell
• MGI ID: MGI:5305426
• Synonyms: gamma-cat^flox
• Gene: Jup Location: Chr11:100259784-100288589 bp, - strand Genetic Position: Chr11, 63.47 cM
• Alliance: Jup^tm1.1Tmj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:178688
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3. An FRT-flanked neo cassette with a 5' loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the neo cassette and left exons 3 through 5 floxed. (J:178688)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Jup Mutation: 162 strains or lines available

References

• Original: J:178688 Demireva EY, et al., Motor neuron position and topographic order imposed by beta- and gamma-catenin activities. Cell. 2011 Oct 28;147(3):641-52
• All: 5 reference(s)