Id2^tm2.1Ago
Targeted Allele Detail

Summary

• Symbol: Id2^tm2.1Ago
• Name: inhibitor of DNA binding 2; targeted mutation 2.1, Ananda W Goldrath
• MGI ID: MGI:5305687
• Synonyms: Id2^Y, Id2-YFP
• Gene: Id2 Location: Chr12:25143798-25146091 bp, - strand Genetic Position: Chr12, 8.57 cM, cytoband B
• Alliance: Id2^tm2.1Ago page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:179006
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: An YFP, 3x STOP sequences, and floxed neo cassette were inserted into exon 1 downstream of the translation initiation start site. Cre-mediated recombination removed the neo cassette. (J:179006)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Id2 Mutation: 21 strains or lines available

References

• Original: J:179006 Yang CY, et al., The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets. Nat Immunol. 2011 Dec;12(12):1221-9
• All: 11 reference(s)