Gt(ROSA)26Sor^{tm1(CAG-Bmpr1a)Que}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-Bmpr1a)Que}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Jianwen Que
• MGI ID: MGI:5305709
• Synonyms: Rosa26^{CAG-loxpstoploxp-caBmpr1a}
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-Bmpr1a)Que} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:166768
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Constitutively active, Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(CAG-Bmpr1a)Que} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Bmpr1a (MGI:1338938)

• Mutation details: A CAG promoter was placed upstream of a floxed neomycin, 4X polyA cassette which was followed in turn by a Bmpr1a, polyA construct. A single glutamine to aspartic acid substitution is present in the glycine-serine domain. (J:166768)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 994 strains or lines available

References

• Original: J:166768 Rodriguez P, et al., BMP signaling in the development of the mouse esophagus and forestomach. Development. 2010 Dec;137(24):4171-6
• All: 6 reference(s)