Gak^tm2Legr
Targeted Allele Detail

Summary

• Symbol: Gak^tm2Legr
• Name: cyclin G associated kinase; targeted mutation 2, Lois E Greene
• MGI ID: MGI:5305733
• Synonyms: GAK^fl
• Gene: Gak Location: Chr5:108717277-108777621 bp, - strand Genetic Position: Chr5, 53.2 cM
• Alliance: Gak^tm2Legr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:180119
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1. A floxed neo cassette was inserted downstream of exon 1. (J:180119)

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gak Mutation: 60 strains or lines available

References

• Original: J:180119 Lee DW, et al., Essential role of cyclin-G-associated kinase (Auxilin-2) in developing and mature mice. Mol Biol Cell. 2008 Jul;19(7):2766-76
• All: 3 reference(s)