In(2Lnp-Itga6)47Ddu
Targeted Allele Detail

Summary

• Symbol: In(2Lnp-Itga6)47Ddu
• Name: inversion, Chr 2, Denis Duboule 47
• MGI ID: MGI:5305739
• Synonyms: HoxD^{Inv(rel5-Itga6)}, Inv(rel5-Itga6)
• Gene: In(2Lnp-Itga6)47Ddu Location: Chr2:71617230-74409779 bp Genetic Position: Chr2, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:178930
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion
• In(2Lnp-Itga6)47Ddu involves 67 genes/genome features (Gm11084, Gm25960, Zakit ...) View all
• Mutation details: A 2.7 Mb inversion was induced by cre mediated recombination between Is(2)46Ddu and Itga6^tm1Son (J:178930)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any In(2Lnp-Itga6)47Ddu Mutation: 0 strains or lines available

References

• Original: J:178930 Montavon T, et al., A regulatory archipelago controls hox genes transcription in digits. Cell. 2011 Nov 23;147(5):1132-45
• All: 4 reference(s)