Mir34a^tm1.1Aven
Targeted Allele Detail

Summary

• Symbol: Mir34a^tm1.1Aven
• Name: microRNA 34a; targeted mutation 1.1, Andrea Ventura
• MGI ID: MGI:5305966
• Gene: Mir34a Location: Chr4:150152911-150153012 bp, + strand Genetic Position: Chr4, 80.85 cM
• Alliance: Mir34a^tm1.1Aven page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:180144
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The complete sequence was floxed. Cre mediated recombination removed the coding sequence. (J:180144)

Expression

In Mice Carrying this Mutation:

44 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir34a Mutation: 9 strains or lines available

References

• Original: J:180144 Agostini M, et al., microRNA-34a regulates neurite outgrowth, spinal morphology, and function. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21099-104
• All: 6 reference(s)