Mboat4^tm2Vlcg
Targeted Allele Detail

Summary

• Symbol: Mboat4^tm2Vlcg
• Name: membrane bound O-acyltransferase domain containing 4; targeted mutation 2, Velocigene
• MGI ID: MGI:5305990
• Gene: Mboat4 Location: Chr8:34582184-34592336 bp, + strand Genetic Position: Chr8, 20.9 cM
• Alliance: Mboat4^tm2Vlcg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:180107
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire coding region was replaced with a lacZ gene and neo cassette via homologous recombination. RT-PCR confirmed the absence of transcript expression in pituitary gland, stomach, and small intestine. (J:180107)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mboat4 Mutation: 18 strains or lines available

References

• Original: J:180107 Kang K, et al., Mouse ghrelin-O-acyltransferase (GOAT) plays a critical role in bile acid reabsorption. FASEB J. 2012 Jan;26(1):259-71
• All: 1 reference(s)