Snrpe^M1157Lja
Chemically induced Allele Detail

Summary

• Symbol: Snrpe^M1157Lja
• Name: small nuclear ribonucleoprotein E; mutation 1157, J Larry Jameson
• MGI ID: MGI:5306139
• Synonyms: 1157
• Gene: Snrpe Location: Chr1:133531609-133538018 bp, - strand Genetic Position: Chr1, 57.94 cM
• Alliance: Snrpe^M1157Lja page

Hypogonadism with ongoing spermatogenesis in Snrpe^M1157Lja/Snrpe⁺ mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU induced a T227A mutation resulting in a glutamic acid to aspartic acid amino acid substitution at position 51 (E51D). (J:179895)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Snrpe Mutation: 8 strains or lines available

References

• Original: J:179895 Weiss J, et al., ENU mutagenesis in mice identifies candidate genes for hypogonadism. Mamm Genome. 2012 Jun;23(5-6):346-55
• All: 1 reference(s)