Ephb1^tm1.1Henk
Targeted Allele Detail

Summary

• Symbol: Ephb1^tm1.1Henk
• Name: Eph receptor B1; targeted mutation 1.1, Mark Henkmeyer
• MGI ID: MGI:5306414
• Synonyms: EphB1^T-lacZ
• Gene: Ephb1 Location: Chr9:101799327-102231892 bp, - strand Genetic Position: Chr9, 54.15 cM
• Alliance: Ephb1^tm1.1Henk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:176056
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A lacZ was inserted in frame within exon 9 immediately following codon 578. Cre-mediated recombination removed the floxed neo cassette. (J:176056, J:184158)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ephb1 Mutation: 43 strains or lines available

References

• Original: J:176056 Thakar S, et al., Critical roles for EphB and ephrin-B bidirectional signalling in retinocollicular mapping. Nat Commun. 2011;2:431
• All: 5 reference(s)