Cbx8^tm1.1Hko
Targeted Allele Detail

Summary

• Symbol: Cbx8^tm1.1Hko
• Name: chromobox 8; targeted mutation 1.1, Haruhiko Koseki
• MGI ID: MGI:5306630
• Synonyms: Cbx8^delta
• Gene: Cbx8 Location: Chr11:118929262-118931739 bp, - strand Genetic Position: Chr11, 83.33 cM, cytoband E2
• Alliance: Cbx8^tm1.1Hko page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:178955
• Parent Cell Line: M1/M-1 (ES Cell)
• Strain of Origin: (129 x C57BL/6)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed exons 2 through 4. (J:178955)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cbx8 Mutation: 18 strains or lines available

References

• Original: J:178955 Tan J, et al., CBX8, a Polycomb Group Protein, Is Essential for MLL-AF9-Induced Leukemogenesis. Cancer Cell. 2011 Nov 15;20(5):563-75
• All: 1 reference(s)