Casr^tm1Wch
Targeted Allele Detail

Summary

• Symbol: Casr^tm1Wch
• Name: calcium-sensing receptor; targeted mutation 1, Wenhan Chang
• MGI ID: MGI:5306665
• Synonyms: Casr^flox
• Gene: Casr Location: Chr16:36314058-36382503 bp, - strand Genetic Position: Chr16, 25.57 cM
• Alliance: Casr^tm1Wch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:180651
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted upstream of exon 7. An additional loxP site was inserted downstream of exon 7. (J:180651)

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Casr Mutation: 61 strains or lines available

References

• Original: J:180651 Chang W, et al., The extracellular calcium-sensing receptor (CaSR) is a critical modulator of skeletal development. Sci Signal. 2008;1(35):ra1
• All: 19 reference(s)