Bicral^{Gt(M019E03)Wrst}
Gene trapped Allele Detail

Summary

• Symbol: Bicral^{Gt(M019E03)Wrst}
• Name: BRD4 interacting chromatin remodeling complex associated protein like; gene trap M019E03, German Gene Trap Consortium
• MGI ID: MGI:5306775
• Synonyms: M019E03
• Gene: Bicral Location: Chr17:47109046-47169408 bp, - strand Genetic Position: Chr17, 22.9 cM
• Alliance: Bicral^{Gt(M019E03)Wrst} page

Mutation origin

• Mutant Cell Line: M019E03
• Germline Transmission: Earliest citation of germline transmission: J:85162
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: This mutation was induced by retroviral transduction of ES cells with the U3betageo gene trap vector, which contains a promoterless E. coli beta-galactosidase (lacZ)/neomycin phosphotransferase fusion gene (betageo) without a splice acceptor sequence. Its insertion has disrupted intron 5 of the endogenous gene. (J:82809)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bicral Mutation: 319 strains or lines available

References

• Original: J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
• All: 2 reference(s)