Npy1r^tm1.2Ceva
Targeted Allele Detail

Summary

• Symbol: Npy1r^tm1.2Ceva
• Name: neuropeptide Y receptor Y1; targeted mutation 1.2, Carola Eva
• MGI ID: MGI:5307899
• Gene: Npy1r Location: Chr8:67149844-67159444 bp, + strand Genetic Position: Chr8, 33.15 cM, cytoband B3-C2
• Alliance: Npy1r^tm1.2Ceva page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:180396
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: Cre-mediated recombination removed the coding region. Immunohistochemistry confirmed the absence of protein expression. (J:180396)

Generation of the Npy1r^tm1.1Ceva and Npy1r^tm1.2Ceva alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Npy1r Mutation: 25 strains or lines available

References

• Original: J:180396 Bertocchi I, et al., Regulatory functions of limbic Y1 receptors in body weight and anxiety uncovered by conditional knockout and maternal care. Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19395-400
• All: 2 reference(s)