Rgs18^m1H
Chemically induced Allele Detail

Summary

• Symbol: Rgs18^m1H
• Name: regulator of G-protein signaling 18; mutation 1, Harwell
• MGI ID: MGI:5307901
• Synonyms: BHV48, RGS18^-
• Gene: Rgs18 Location: Chr1:144628430-144651165 bp, - strand Genetic Position: Chr1, 62.99 cM
• Alliance: Rgs18^m1H page

Mutation origin

• Strain of Origin: BALB/cAnN
• Project Collection: Harwell ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• Mutation details: The mutation was identified in a screen of the Harwell ENU mutant archive for mutations in this gene. The molecular lesion is a T to A (TAT to TAA) mutation that results in a premature stop codon (Y139STOP) in exon 4. Western blot analysis confirmed the absence of protein expression in platelet extracts from homozygous mutant mice. (J:169366)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Rgs18 Mutation: 24 strains or lines available

References

• Original: J:169366 MouseBook^TM, Information obtained from MouseBook^TM, Medical Research Council Mammalian Genetics Unit, Harwell, UK. Unpublished. 2005-2013
• All: 2 reference(s)