Nrn1^tm1.2Ndiv
Targeted Allele Detail

Summary

• Symbol: Nrn1^tm1.2Ndiv
• Name: neuritin 1; targeted mutation 1.2, Elly Nedivi
• MGI ID: MGI:5307918
• Gene: Nrn1 Location: Chr13:36909596-36918451 bp, - strand Genetic Position: Chr13, 14.44 cM
• Alliance: Nrn1^tm1.2Ndiv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:178970
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2 and a loxP and FRT flanked neo cassette was inserted downstream of exon 3 via homologous recombination. Recombinase mediated recombination removed the neo cassette and exons 2 and 3. (J:178970)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nrn1 Mutation: 18 strains or lines available

References

• Original: J:178970 Fujino T, et al., CPG15 regulates synapse stability in the developing and adult brain. Genes Dev. 2011 Dec 15;25(24):2674-85
• All: 7 reference(s)