Esco2^tm1.2Ge
Targeted Allele Detail

Summary

• Symbol: Esco2^tm1.2Ge
• Name: establishment of sister chromatid cohesion N-acetyltransferase 2; targeted mutation 1.2, Gregor Eichele
• MGI ID: MGI:5308063
• Gene: Esco2 Location: Chr14:66056476-66071418 bp, - strand Genetic Position: Chr14, 34.36 cM, cytoband D1
• Alliance: Esco2^tm1.2Ge page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:180371
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination of Esco2^tm1.1Ge removed exons 2 and 3. (J:180371)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Esco2 Mutation: 37 strains or lines available

References

• Original: J:180371 Whelan G, et al., Cohesin acetyltransferase Esco2 is a cell viability factor and is required for cohesion in pericentric heterochromatin. EMBO J. 2012 Jan 4;31(1):71-82
• All: 3 reference(s)