Tsc22d3^tm1.1Ric
Targeted Allele Detail

Summary

• Symbol: Tsc22d3^tm1.1Ric
• Name: TSC22 domain family, member 3; targeted mutation 1.1, Carlo Riccardi
• MGI ID: MGI:5308358
• Synonyms: Gilz KO
• Gene: Tsc22d3 Location: ChrX:139440277-139501257 bp, - strand Genetic Position: ChrX, 61.35 cM, cytoband F1
• Alliance: Tsc22d3^tm1.1Ric page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:179667
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: One loxP site was inserted upstream of exon 6 and a second loxP was placed downstream. An FRT flanked neomycin cassette was located further downstream. Exon 6 was then excised in properly targeted mice. (J:179667)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tsc22d3 Mutation: 5 strains or lines available

References

• Original: J:179667 Bruscoli S, et al., Long Glucocorticoid-induced Leucine Zipper (L-GILZ) Protein Interacts with Ras Protein Pathway and Contributes to Spermatogenesis Control. J Biol Chem. 2012 Jan 6;287(2):1242-51
• All: 5 reference(s)