Gt(ROSA)26Sor^tm4Sia
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm4Sia
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 4, Shinichi Aizawa
• MGI ID: MGI:5308560
• Synonyms: Gt(ROSA)26Sor^{tm4(HIST1H2BB/mKeima-Red)Sia}, R26R-H2B-mKeima-Red
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm4Sia page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:180918
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A vector, which contains (5' to 3') a splice acceptor, floxed neo/stop cassette and the C-terminus of the nuclear human H2B fused to the mCKeima-Red reporter, was inserted into the locus. (J:180918)

Conditional targeting of the ROSA26 locus to generate various reporter lines

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:180918 Abe T, et al., Establishment of conditional reporter mouse lines at ROSA26 locus for live cell imaging. Genesis. 2011 Jul;49(7):579-90
• All: 1 reference(s)