Akap13^tm1Segj
Targeted Allele Detail

Summary

• Symbol: Akap13^tm1Segj
• Name: A kinase anchor protein 13; targeted mutation 1, James H Segars
• MGI ID: MGI:5308769
• Synonyms: brx^-
• Gene: Akap13 Location: Chr7:75105282-75404357 bp, + strand Genetic Position: Chr7, 43.76 cM, cytoband D1
• Alliance: Akap13^tm1Segj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:111574
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo cassette replaced exon 5, which encodes the Dbl homology (DH) domain. RT-PCR confirmed the absence of transcript expression in embryos. (J:181088)

Expression

In Mice Carrying this Mutation:	24 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Akap13 Mutation: 178 strains or lines available

References

• Original: J:111574 Kino T, et al., Rho family Guanine nucleotide exchange factor Brx couples extracellular signals to the glucocorticoid signaling system. J Biol Chem. 2006 Apr 7;281(14):9118-26
• All: 5 reference(s)