Adamts18^tm1Zdl
Targeted Allele Detail

Summary

• Symbol: Adamts18^tm1Zdl
• Name: ADAM metallopeptidase with thrombospondin type 1 motif 18; targeted mutation 1, Zongdong Li
• MGI ID: MGI:5308778
• Synonyms: ADAMTS-18^loxP
• Gene: Adamts18 Location: Chr8:114423758-114575370 bp, - strand Genetic Position: Chr8, 59.65 cM
• Alliance: Adamts18^tm1Zdl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:181091
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert a loxP site upstream of exon 5, followed by a frt-flanked neomycin resistance (neo) cassette, and a second loxP site downstream of exon 6 of the a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18 (Adamts18) gene. (J:181091)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Adamts18 Mutation: 65 strains or lines available

References

• Original: J:181091 Li Z, Direct Data Submission 2012/03/08. MGI Direct Data Submission. 2012
• All: 1 reference(s)