Tg(H2-Ea-LACK)1Ngkh
Transgene Detail
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| Symbol: |
Tg(H2-Ea-LACK)1Ngkh |
| Name: |
transgene insertion 1, Nicolas Glaichenhaus |
| MGI ID: |
MGI:5311331 |
| Synonyms: |
IE-LACK |
| Transgene: |
Tg(H2-Ea-LACK)1Ngkh Location: unknown
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| Alliance: |
Tg(H2-Ea-LACK)1Ngkh page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: A truncated cDNA encoding the Leishmania major activated protein kinase C receptor (LACK) with an N-terminal hemagglutinin (HA) epitope was placed under control of the promoter of the mouse MHC type II I-Ealpha promoter (k allele). LACK transcripts are detected in primary and secondary lymphoid organs, including thymus, spleen and bone marrow, but not in liver, kidney or muscle of transgenic mice.
(J:181384)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 2 strains available
Cell Lines: 0 lines available
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| Original: |
J:181384 Julia V, et al., Resistance to Leishmania major induced by tolerance to a single antigen. Science. 1996 Oct 18;274(5286):421-3 |
| All: |
2 reference(s) |
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Analysis Tools
