b2b954Clo
Chemically induced Allele Detail

Summary

• Symbol: b2b954Clo
• Name: Mutant line 954; Bench to Bassinet Program (B2B/CVDC), mutation 954 Cecilia Lo
• MGI ID: MGI:5311368
• Synonyms: Rudolph
• Gene: b2b954Clo Location: unknown
• Alliance: b2b954Clo page

Nasal hemorrhage

Show the 13 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: B2B/CvDC

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Undefined
• This ENU-induced mutation was isolated in a screen at the University of Pittsburgh.

Disease models

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any b2b954Clo Mutation: 1 strain or line available

Notes

Summative Diagnosis:
Cardiovascular defects: Persistent truncus arteriosus (PTA) Type I and aortic arch anomalies such as right aortic arch (RAA), vascular ring and ventricular septal defect (VSD)
Noncardiovascular defects: Thymic hypoplasia and nasal hemorrhage.

Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (http://www.ipccc.net/).

Fyler Code ID	Code Description
0500	Truncus arteriosus
1300	Ventricular septal defect
2720	Right aortic arch
2760	Vascular ring
3804	Congenital heart disease
4610	DiGeorge syndrome
4906	Non-cardiac abnormality

References

• Original: J:175213 Lo C, Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC). MGI Direct Data Submission (B2B/CvDC). 2011-09-12
• All: 2 reference(s)