Ebi3^tm1Nkma
Targeted Allele Detail

Summary

• Symbol: Ebi3^tm1Nkma
• Name: Epstein-Barr virus induced gene 3; targeted mutation 1, Hitoshi Nakashima
• MGI ID: MGI:5312675
• Gene: Ebi3 Location: Chr17:56259640-56264022 bp, + strand Genetic Position: Chr17, 29.08 cM
• Alliance: Ebi3^tm1Nkma page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:181669
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The first exon containing a methionine codon was replaced with a neomycin resistance cassette. (J:181669)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ebi3 Mutation: 12 strains or lines available

References

• Original: J:181669 Igawa T, et al., Deficiency in EBV-induced gene 3 (EBI3) in MRL/lpr mice results in pathological alteration of autoimmune glomerulonephritis and sialadenitis. Mod Rheumatol. 2009;19(1):33-41
• All: 6 reference(s)