Fzd4^tm1.1Lex
Targeted Allele Detail

Summary

• Symbol: Fzd4^tm1.1Lex
• Name: frizzled class receptor 4; targeted mutation 1.1, Lexicon Genetics
• MGI ID: MGI:5312687
• Gene: Fzd4 Location: Chr7:89053574-89062341 bp, + strand Genetic Position: Chr7, 49.32 cM
• Alliance: Fzd4^tm1.1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:181399
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed exon 2. (J:181399)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fzd4 Mutation: 31 strains or lines available

References

• Original: J:181399 Paes KT, et al., Frizzled 4 is required for retinal angiogenesis and maintenance of the blood-retina barrier. Invest Ophthalmol Vis Sci. 2011 Aug;52(9):6452-61
• All: 1 reference(s)