Bmp7^tm1Jfm
Targeted Allele Detail

Summary

• Symbol: Bmp7^tm1Jfm
• Name: bone morphogenetic protein 7; targeted mutation 1, James F Martin
• MGI ID: MGI:5312860
• Gene: Bmp7 Location: Chr2:172709805-172782114 bp, - strand Genetic Position: Chr2, 95.54 cM
• Alliance: Bmp7^tm1Jfm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:181229
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site and FRT flanked neo cassette were inserted upstream of exon 4 and a loxP site was inserted downstream of exon 4 via homologous recombination. (J:199300)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bmp7 Mutation: 37 strains or lines available

References

• Original: J:181229 Bonilla-Claudio M, et al., Bmp signaling regulates a dose-dependent transcriptional program to control facial skeletal development. Development. 2012 Feb;139(4):709-19
• All: 5 reference(s)