Nhlrc1^tm1.2Geno
Targeted Allele Detail

Summary

• Symbol: Nhlrc1^tm1.2Geno
• Name: NHL repeat containing 1; targeted mutation 1.2, Genoway
• MGI ID: MGI:5312925
• Synonyms: Epm2b^-
• Gene: Nhlrc1 Location: Chr13:47166033-47168326 bp, - strand Genetic Position: Chr13, 24.5 cM
• Alliance: Nhlrc1^tm1.2Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:181559
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed the neo cassette and coding exon. (J:181559)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nhlrc1 Mutation: 16 strains or lines available

References

• Original: J:181559 Criado O, et al., Lafora bodies and neurological defects in malin-deficient mice correlate with impaired autophagy. Hum Mol Genet. 2012 Apr 1;21(7):1521-33
• All: 11 reference(s)