Clec9a^tm1.1Kens
Targeted Allele Detail

Summary

• Symbol: Clec9a^tm1.1Kens
• Name: C-type lectin domain family 9, member a; targeted mutation 1.1, Ken Shortman
• MGI ID: MGI:5313299
• Gene: Clec9a Location: Chr6:129385825-129401726 bp, + strand Genetic Position: Chr6, 63.3 cM
• Alliance: Clec9a^tm1.1Kens page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:181366
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 5 was flanked by loxP sites and a PGK-neomycin selection cassette was inserted in a neighboring intron. The selection cassette was subsequently removed by crossing mice to a cre expressing mouse. (J:181366)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clec9a Mutation: 29 strains or lines available

References

• Original: J:181366 Caminschi I, et al., Antibody responses initiated by Clec9A-bearing dendritic cells in normal and Batf3(-/-) mice. Mol Immunol. 2012 Feb;50(1-2):9-17
• All: 2 reference(s)