Tgfb3^tm1Moaz
Targeted Allele Detail

Summary

• Symbol: Tgfb3^tm1Moaz
• Name: transforming growth factor, beta 3; targeted mutation 1, Mohamad Azhar
• MGI ID: MGI:5313415
• Synonyms: Tgfb3^cko
• Gene: Tgfb3 Location: Chr12:86103519-86125815 bp, - strand Genetic Position: Chr12, 40.09 cM
• Alliance: Tgfb3^tm1Moaz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:181226
• Parent Cell Line: KG-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site and an FRT flanked MC1-neomycin selection cassette were inserted in intron 5 and a second loxP site was placed in intron 6. (J:181226)

Expression

In Mice Carrying this Mutation:

1 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tgfb3 Mutation: 35 strains or lines available

References

• Original: J:181226 Doetschman T, et al., Generation of mice with a conditional allele for the transforming growth factor beta3 gene. Genesis. 2012 Jan;50(1):59-66
• All: 5 reference(s)