Gt(ROSA)26Sor^{tm10(Lmp1)Rsky}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm10(Lmp1)Rsky}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 10, Klaus Rajewsky
• MGI ID: MGI:5314029
• Synonyms: LMP1^flSTOP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm10(Lmp1)Rsky} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:181546
• Parent Cell Line: BALB/c-I (ES Cell)
• Strain of Origin: BALB/cJ

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The construct containing (5' to 3') a splice acceptor, floxed neo stop cassette and EBV B95-8 strain Lmp1 coding sequence was inserted into the locus. (J:181546)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:181546 Zhang B, et al., Immune Surveillance and Therapy of Lymphomas Driven by Epstein-Barr Virus Protein LMP1 in a Mouse Model. Cell. 2012 Feb 17;148(4):739-51
• All: 3 reference(s)